Clinical Client Cases
白血病
弥漫性内生性脑胶质瘤(DIPG)
膀胱癌
脑胶质瘤
增生性小圆细胞瘤(DSRCT)
案例背景​
1. 患者病情概况
·  患者于案例服务前 3 年被确诊为罕见慢性白血病(血癌),此前已在国内多家医疗机构接受治       疗,但病情未获显著改善。​2017 年,患者病情突发恶化,被转诊至国内优质肿瘤专科医院。​
2. 服务需求发起​
·  国内优质肿瘤专科医院专家为获取国际先进治疗思路、控制患者病情、寻求更优治疗方案,向华     美浩联(E-Health Now)正式提出国际医疗服务申请,核心需求为连接美国血液领域专家。
华美浩联(E-Health Now)服务执行流程
1. 前期资料准备与处理​
·  患者及家属通过华美浩联平台完成用户注册,提交病情简述,并上传核心医疗文件(包括病例、     化验报告扫描件、血液涂片高清图像等)。​
·  华美浩联立即启动专业医疗翻译服务,将所有中文医疗资料精准翻译为英文,确保国际专家可清     晰解读。
2. 国际专家匹配与预约​
·  针对 “罕见病领域专家匹配难度高” 的痛点,华美浩联通过专业筛选与对接,在 3 个工作日内     成功预约到该罕见慢性白血病领域具有全球高影响力的美国血液专家。​
3. 远程会诊实施​
·  预约完成后,于同周内通过华美浩联平台,组织患者、国内主治医生与美国专家开展三方远程会     诊,聚焦患者病情深度研讨。​
4. 会诊报告交付​
·  远程会诊结束后,在 8 小时内向患者及国内主治医生同步交付中英文版本的《综合诊疗建议报       告》,确保建议可快速落地参考。
后续服务与病情跟进
·  会诊结束后,华美浩联通过安全数字平台搭建长期沟通通道,保障患者、国内医生与美国专家的     持续联络。​
·  会诊完成两周后,应患者及国内专家需求,华美浩联协助再次向同一位美国专家发起咨询申请,     针对患者最新生理检测结果进行补充讨论,进一步优化治疗方案。
·  患者本人、患者家属及国内主治专家对华美浩联的服务质量(包括响应速度、专家匹配精准度、     报告交付效率)及最终服务成果给予一致好评,并主动推荐该服务。
患者概况
患者, 13岁, 2017年9月底出现有复视,行走时无法保持平衡,以及吞咽困难。患者接受了头部的CT扫描,显示其脑干有病变。然后患者接受了脑部MRI,症状和影像结果与弥漫性内生性脑桥胶质瘤(DIPG)一致。曾在国内多家专业医疗机构诊治,不见成效。由国内知名专科医院专家向华美浩联提出服务申请,希望咨询美国脑胶质瘤专家以了解国外的方案建议,及时控制病情。
后续更新
专家给出了几个可行的方案,经多方讨论,决定使用目前CED治疗技术,并决定协调安排赴美就医。患者、患者家属以及中方专家都对华美浩联服务的质量和结果表示一致的满意与好评。通过华美浩联的安全数字平台,患者、中方医生和美国专家保持联络。一个半月后等患者在国内做完预先的放疗疗程及检测,在华美浩联的协助下,患者及其家属顺利赴美接受后续治疗。
华美浩联(E-Health Now)操作流程
患者和患者家属在华美浩联平台上注册,提供病情简述,和上传所需文件:病历和化验报告扫描件,脑部核磁共振等。华美浩联开始进行专业医疗翻译。虽病况罕见,寻找国际专家的挑战性高,但在华美浩联专业人士的量身服务下,成功在三个工作日内预约到两位在此罕见病领域的全球有极高影响力的美国小儿脑胶质瘤专家。同周内,在华美浩联的平台上完成了聚集国际专家的远程咨询。会诊完成八个小时内,患者和中国医生收到中英文的量身方案和报告。
患者概况
膀胱癌患者,男性,55岁,膀胱多发肿瘤,就先手术还是先化疗方案的问题,中国医生存在争议,患者求助E-Health Now寻求国外专家建议,希望连接美国泌尿肿瘤专家,以了解国外的治疗建议,控制病情,并且为患者推荐先进疗法和治疗建议。
华美浩联(E-Health Now)操作流程
由E-Health Now在4个工作日内,邀请美国丹娜法伯癌症中心的泌尿内、外科两位主任Dr. Bradley McGregor和Dr. Adam Stuart Kibel,联合北京大学第一医院、中国医学科学院肿瘤医院、上海交通大学医学院附属仁济医院、重庆新桥医院来自肿瘤内科、泌尿外科、医学影像科等多个领域共计10位国内外专家,参与此次中美远程多学科咨询。此次会诊结合现有检查资料,两位美国专家一致认为,术前新辅助化疗对病人生存获益是有利的,目前没有明确证据证明术后化疗对病人的生存有益,并且进行全膀胱切除术后有50%的患者不能耐受化疗,所以建议首先进行术前新辅助化疗。中国多位医生在咨询中也提出了各自观点和疑问,咨询完成四十八个小时内,患者和中国医生收到中英文的量身治疗方案建议。
后续更新
会诊结束后,患者根据美国专家建议,并参考中国专家团队意见,终达成一致,改变国内原有的治疗方案,采取术前先行化疗方案,再择期手术。会诊结果得到了患者、家属、中方专家的认可。
患者概况
脑胶质瘤患者, 男性,42岁,诊断为少突星形细胞瘤并实施肿瘤切除术,患者及家属联系E-Health Now,寻求指定美国MD安德森癌症中心的专家,目前急于赴美接受质子治疗,想了解相关具体综合治疗方案以及预计生存周期。
华美浩联(E-Health Now)操作流程
首先,协助患者在华美浩联平台上注册用户,并将病历资料翻译成英文,协助去执行手术的医院取得DICOM影像资料,并上传到系统。E-Health Now在三个工作日内,联络了MD安德森癌症中心神经肿瘤内科主任Dr. John F. de Groot,与中国医院内神经肿瘤领域的主任医师进行中美远程多学科咨询。美方专家发表意见认为目前病情比较稳定,可保持密切观察或者考虑质子治疗及其他药物治疗,术后6-9个月后都可进行,有效的治疗能够延长患者生存期,减少对大脑的毒性作用,尤其是对于年轻的患者。会诊完成四十八个小时内,患者和中国医生收到中英文的量身治疗建议。
后续更新
会诊结束后,患者及家属积极准备赴美就医的手续申办,并决定赴美就医接受后续治疗,中外医生及患者家属对于E-Health Now服务的效率和质量表示满意。
患者概况
促结缔组织增生性小圆细胞瘤(DSRCT)患者, 男性,26岁,因腹部绞痛逐渐加重,进行检查诊断为间叶源性肿瘤,是一种罕见的高度恶性、具侵袭性的肿瘤,全世界自发现该病以来仅诊断出约200多病例。患者及家属在国内多家医院进行治疗后,希望寻求美国肉瘤研究专家的诊疗意见。
华美浩联(E-Health Now)操作流程
首先,协助患者在华美浩联平台上注册用户,并将病历资料翻译成英文,并上传到系统。E-Health Now在三个工作日内,联络了Dr. Sant P Chawla,Dr. Sant P Chawla教授是南加州Sarcoma肿瘤中心主任,MD安德森癌症中心教授,多年来一直从事肉瘤相关的研究。同时邀请了北京大学第一医院肿瘤化疗科主任进行中美远程咨询。根据病人前后CT影像进展对比,认为患者目前病情总体稳定,一些病灶轻微进展。中美医生达成一致治疗意见:继续原化疗药物治疗,加用PD-1抑制剂,6个月后复查CT。如治疗无效,可考虑到美国去参加新药物Yondelis临床试验。会诊完成四十八个小时内,患者和中国医生收到中英文的量身治疗建议。
后续更新
患者及家属与国内外多位知名肿瘤医生会诊后,决定开始尝试加入PD-1治疗,治疗效果随时跟进。中外医生及患者家属对于E-Health Now服务的效率和质量表示满意。
Case 1: Leukemia
Case 2: Diffuse Intrinsic Pontine Glioma (DIPG)
Case 3: Bladder Cancer
Case 4: Glioma
Case 5: Desmoplastic Small Round Cell Tumor (DSRCT)
Case Background

(1) Patient Condition Overview: The patient was diagnosed with a rare chronic leukemia (blood cancer) three years before the case service, having received treatment at multiple domestic medical institutions without significant improvement. In 2017, the patient's condition suddenly deteriorated and he was transferred to a leading domestic oncology specialty hospital.

(2) Service Need Initiation: To obtain advanced international treatment ideas, control the patient's condition, and seek better treatment plans, experts from the leading domestic oncology specialty hospital formally applied to E-Health Now for international medical services, with the core need being to connect with American hematology experts.

E-Health Now Service Execution Process

(1) Preliminary Document Preparation and Processing:

· The patient and family completed user registration on the E-Health Now platform, submitted a brief condition description, and uploaded core medical documents (including case files, scanned laboratory reports, high-definition images of blood smears, etc.).

· E-Health Now immediately initiated professional medical translation services, accurately translating all Chinese medical materials into English to ensure clear interpretation by international experts.

(2) International Expert Matching and Scheduling:

· Addressing the pain point of "high difficulty in matching rare disease experts," E-Health Now, through professional screening and coordination, successfully scheduled an American hematology expert with global influence in the rare chronic leukemia field within three business days.

(3) Remote Consultation Implementation:

· After scheduling, a three-party remote consultation among the patient, attending Chinese physician, and American expert was organized on the E-Health Now platform within the same week, focusing on in-depth discussion of the patient's condition.

(4) Consultation Report Delivery:

· Within 8 hours after the remote consultation, the Comprehensive Diagnosis and Treatment Recommendation Report was delivered to the patient and attending Chinese physician in both Chinese and English, ensuring rapid implementation of recommendations.

Follow-up Services and Condition Monitoring

· After the consultation, E-Health Now established a long-term communication channel through its secure digital platform to ensure ongoing contact among the patient, domestic doctors, and American experts.

· Two weeks after the consultation, at the request of the patient and domestic experts, E-Health Now assisted in initiating a second consultation with the same American expert to discuss the patient's latest physiological test results and further optimize the treatment plan.

· The patient, family members, and attending Chinese experts gave unanimous praise for E-Health Now's service quality (including response speed, expert matching accuracy, and report delivery efficiency) and the final service outcomes, and actively recommended the service.

Patient Profile

A 13-year-old patient developed diplopia, inability to maintain balance while walking, and dysphagia at the end of September 2017. A CT scan of the head revealed a lesion in the brainstem, and a subsequent brain MRI confirmed the symptoms and imaging findings were consistent with Diffuse Intrinsic Pontine Glioma (DIPG). After unsuccessful treatment at several specialized medical institutions in China, a renowned domestic specialist applied to E-Health Now for service, hoping to consult American glioma experts for overseas treatment recommendations and timely disease control.

Follow-up Update

The experts offered several feasible options. After multi-party discussion, it was decided to use the current CED (Convection Enhanced Delivery) treatment technology and to arrange for overseas treatment in the United States. The patient, family members, and Chinese experts all expressed unanimous satisfaction and praise for the quality and outcomes of E-Health Now's service. Through E-Health Now's secure digital platform, the patient, Chinese physicians, and American experts maintained contact. After the patient completed the pre-treatment radiotherapy course and examinations domestically in approximately one and a half months, the patient and family successfully went to the United States for follow-up treatment with E-Health Now's assistance.

E-Health Now Workflow

The patient and family registered on the E-Health Now platform, submitted a brief condition description, and uploaded the required documents: scanned medical records and laboratory reports, brain MRI, etc. E-Health Now initiated professional medical translation. Despite the rarity of the condition and the challenges in finding international experts, E-Health Now's professional bespoke service successfully scheduled two globally influential American pediatric glioma experts within three business days. The remote consultation with international experts was completed on the E-Health Now platform within the same week. Within eight hours of the consultation, the patient and Chinese doctors received a tailored plan and report in both Chinese and English.

Patient Profile

A 55-year-old male patient with bladder cancer presented with multiple tumors in the bladder. There was disagreement among Chinese physicians regarding whether to proceed with surgery first or chemotherapy first. The patient turned to E-Health Now for advice from international experts, hoping to be connected with American uro-oncology specialists to learn about overseas treatment recommendations, control the disease, and access advanced therapies and treatment options.

E-Health Now Workflow

Within four business days, E-Health Now invited Dr. Bradley McGregor and Dr. Adam Stuart Kibel, both Chiefs of Urological Internal Medicine and Surgery at Dana-Farber Cancer Institute in the United States, to join a Sino-American remote multidisciplinary consultation. Ten domestic and international experts from Peking University First Hospital, the National Cancer Center/Cancer Hospital of the Chinese Academy of Medical Sciences, Renji Hospital affiliated to Shanghai Jiao Tong University School of Medicine, and Xinqiao Hospital, covering oncology, urology, medical imaging, and other specialties, also participated. Based on the available examination data, both American experts unanimously agreed that neoadjuvant chemotherapy before surgery was beneficial for the patient's survival. There is currently no clear evidence that postoperative chemotherapy benefits patient survival, and 50% of patients cannot tolerate chemotherapy after radical cystectomy. Therefore, they recommended neoadjuvant chemotherapy first. Chinese physicians also raised their own views and questions during the consultation. Within 48 hours after the consultation, the patient and Chinese doctors received a tailored treatment plan in both Chinese and English.

Follow-up Update

After the consultation, based on the American experts' recommendations and the opinions of the Chinese expert team, the patient reached a consensus to change the original domestic treatment plan, adopting neoadjuvant chemotherapy first, followed by elective surgery. The consultation results were recognized by the patient, family members, and Chinese experts.

Patient Profile

A 42-year-old male patient with glioma was diagnosed with oligoastrocytoma and underwent tumor resection. The patient and family contacted E-Health Now, seeking experts from MD Anderson Cancer Center in the United States. The patient was eager to travel to the US for proton therapy and wanted to learn about specific comprehensive treatment plans and estimated survival period.

E-Health Now Workflow

First, E-Health Now assisted the patient in registering on the platform, translated the medical records into English, and helped obtain DICOM imaging data from the hospital where the surgery was performed, uploading it to the system. Within three business days, E-Health Now contacted Dr. John F. de Groot, Chief of Neuro-Oncology at MD Anderson Cancer Center, to conduct a Sino-American remote multidisciplinary consultation with a chief physician specializing in neuro-oncology from a Chinese hospital. The American expert stated that the current condition was relatively stable, and close observation or proton therapy combined with other drug treatments could be considered, both of which can be performed 6-9 months after surgery. Effective treatment can extend the patient's survival and reduce toxicity to the brain, especially for younger patients. Within 48 hours of the consultation, the patient and Chinese doctors received tailored treatment recommendations in both Chinese and English.

Follow-up Update

After the consultation, the patient and family actively prepared the procedures for overseas medical treatment in the United States and decided to go abroad for follow-up treatment. Chinese and foreign doctors, as well as the patient's family, expressed satisfaction with the efficiency and quality of E-Health Now's service.

Patient Profile

A 26-year-old male patient with Desmoplastic Small Round Cell Tumor (DSRCT) presented with progressively worsening abdominal cramps. Examination led to a diagnosis of mesenchymal-origin tumor, a rare and highly malignant, invasive tumor with only approximately 200 cases diagnosed worldwide since its discovery. After treatment at multiple domestic hospitals, the patient and family hoped to seek diagnostic and treatment opinions from American sarcoma research experts.

E-Health Now Workflow

First, E-Health Now assisted the patient in registering on the platform, translated the medical records into English, and uploaded them to the system. Within three business days, E-Health Now contacted Dr. Sant P. Chawla, Professor and Director of the Sarcoma Oncology Center in Southern California, and Professor at MD Anderson Cancer Center, who has been engaged in sarcoma-related research for many years. Simultaneously, the Chief of Oncology Chemotherapy at Peking University First Hospital was invited for a Sino-American remote consultation. Based on comparison of the patient's pre- and post-CT imaging progression, the current condition was assessed as generally stable, with minor progression in some lesions. Chinese and American doctors reached a consensus on treatment: continue the original chemotherapy drugs, add a PD-1 inhibitor, and re-examine with CT after 6 months. If treatment proves ineffective, the patient could consider participating in the Yondelis clinical trial of a new drug in the United States. Within 48 hours of the consultation, the patient and Chinese doctors received tailored treatment recommendations in both Chinese and English.

Follow-up Update

After consulting with multiple renowned oncologists both domestically and internationally, the patient and family decided to start PD-1 treatment, with ongoing monitoring of therapeutic effects. Chinese and foreign doctors, as well as the patient's family, expressed satisfaction with the efficiency and quality of E-Health Now's service.

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